Dan A. Rock: search on Z-Library

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1

Ligand-Based Design of a Potent and Selective Inhibitor of Cytochrome P450 2C19

Foti, Robert S., Rock, Dan A., Han, Xiaogang, Flowers, Robert A., Wienkers, Larry C., Wahlstrom, Jan L.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.10 MB

english, 2012

2

Electroencephalogram, Circulation, and Lung Function After High-Velocity Behind Armor Blunt Trauma

Drobin, Dan, Gryth, Dan, Persson, Jonas K. E., Rocks??n, David, Arborelius, Ulf P., Olsson, Lars-Gunnar, Bursell, Jenny, Kjellstr??m, B Thomas

Journal:

The Journal of Trauma Injury Infection and Critical Care

Year:

2007

Language:

english

File:

PDF, 1.55 MB

english, 2007

3

SPIE Proceedings [SPIE Technical Symposium Southeast - Orlando, FL (Monday 18 May 1987)] Infrared Sensors and Sensor Fusion - Falcon Eye Forward-Looking Infrared (FLIR) System

Rock, Dan, Redus, John, Marr, Lyale, Gohlke, Mark, Hartnett, Doug, Buser, Rudolf G., Warren, Frank B.

Year:

1987

Language:

english

File:

PDF, 2.73 MB

english, 1987

4

Effect of Low Back Pain Risk-Stratification Strategy on Patient Outcomes and Care Processes: the MATCH Randomized Trial in Primary Care

Cherkin, Dan, Balderson, Benjamin, Wellman, Rob, Hsu, Clarissa, Sherman, Karen J., Evers, Sarah C., Hawkes, Rene, Cook, Andrea, Levine, Martin D., Piekara, Diane, Rock, Pam, Estlin, Katherine Talbert,

Journal:

Journal of General Internal Medicine

Year:

2018

Language:

english

File:

PDF, 928 KB

english, 2018

5

Formation of the Active Species of Cytochrome P450 by Using Iodosylbenzene: A Case for Spin-Selective Reactivity

Kyung-Bin Cho, Yohann Moreau, Devesh Kumar, Dan A. Rock, Jeffrey P. Jones, Sason Shaik

Journal:

Chemistry - A European Journal

Year:

2007

Language:

english

File:

PDF, 458 KB

english, 2007

6

Use of Kinetic Isotope Effects to Delineate the Role of Phenylalanine 87 in P450BM-3

Dan A Rock, Anthony E Boitano, Jan L Wahlstrom, Denise A Rock, Jeffrey P Jones

Journal:

Bioorganic Chemistry

Year:

2002

Language:

english

File:

PDF, 2.00 MB

english, 2002

7

Unique ligation properties of eukaryotic NAD+-dependent DNA ligase from Melanoplus sanguinipes entomopoxvirus

Jing Lu, Jie Tong, Hong Feng, Jianmin Huang, Claudio L. Afonso, Dan L. Rock, Francis Barany, Weiguo Cao

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2004

Language:

english

File:

PDF, 804 KB

english, 2004

8

Some computational issues in cluster analysis with no a priori metric

Dan Coleman, Xioapeng Dong, Johanna Hardin, David M. Rocke, David L. Woodruff

Journal:

Computational Statistics & Data Analysis

Year:

1999

Language:

english

File:

PDF, 97 KB

english, 1999

9

Clinical-dosimetric analysis of measures of dysphagia including gastrostomy-tube dependence among head and neck cancer patients treated definitively by intensity-modulated radiotherapy with concurrent chemotherapy

Baoqing Li, Dan Li, Derick H Lau, D Gregory Farwell, Quang Luu, David M Rocke, Kathleen Newman, Jean Courquin, James A Purdy, Allen M Chen

Journal:

Radiation Oncology

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

10

Proteomic analysis of low dose arsenic and ionizing radiation exposure on keratinocytes

Susanne R. Berglund, Alison R. Santana, Dan Li, Robert H. Rice, David M. Rocke, Zelanna Goldberg

Journal:

Year:

2009

Language:

english

File:

PDF, 1004 KB

english, 2009

11

Does the Milky Way launch a large-scale wind?

John E. Everett, Ellen G. Zweibel, Robert A. Benjamin, Dan McCammon, Lindsay Rocks, Donald P. Cox, John S. Gallagher

Journal:

Astrophysics and Space Science

Year:

2007

Language:

english

File:

PDF, 619 KB

english, 2007

12

Hematological and lipid changes in newborn piglets fed milk-replacer diets containing erucic acid

John K. G. Kramer, Frank D. Sauer, Edward R. Farnworth, Dan Stevenson, Gail A. Rock

Journal:

Year:

1998

Language:

english

File:

PDF, 98 KB

english, 1998

13

Advances in predicting CYP-mediated drug interactions in the drug discovery setting

Wahlstrom, Jan L, Rock, Dan A, Slatter, J Greg, Wienkers, Larry C

Journal:

Expert Opinion on Drug Discovery

Year:

2006

Language:

english

File:

PDF, 231 KB

english, 2006

14

Active Site Mutations of Cytochrome P450cam Alter the Binding, Coupling, and Oxidation of the Foreign Substrates (R)- and (S)-2-Ethylhexanol

Kevin J. French, Dan A. Rock, Denise A. Rock, John I. Manchester, Barry M. Goldstein, Jeffrey P. Jones

Journal:

Archives of Biochemistry and Biophysics

Year:

2002

Language:

english

File:

PDF, 180 KB

english, 2002

15

Inexpensive Purification of P450 Reductase and Other Proteins Using 2′,5′-Adenosine Diphosphate Agarose Affinity Columns

Dan Rock, Denise Rock, Jeffrey P. Jones

Journal:

Protein Expression and Purification

Year:

2001

Language:

english

File:

PDF, 28 KB

english, 2001

16

Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors

Hisashi Suzuki, M.Byron Kneller, Dan A Rock, Jeffrey P Jones, William F Trager, Allan E Rettie

Journal:

Archives of Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 568 KB

english, 2004

17

The effects of type II binding on metabolic stability and binding affinity in cytochrome P450 CYP3A4

Chi-Chi Peng, Josh T. Pearson, Dan A. Rock, Carolyn A. Joswig-Jones, Jeffrey P. Jones

Journal:

Archives of Biochemistry and Biophysics

Year:

2010

Language:

english

File:

PDF, 3.48 MB

english, 2010

18

Formation of raloxifene homo-dimer in CYP3A4, evidence for multi-substrate binding in a single catalytically competent P450 active site

John A. Davis, Robert J. Greene, Sean Han, Dan A. Rock, Larry C. Wienkers

Journal:

Archives of Biochemistry and Biophysics

Year:

2011

Language:

english

File:

PDF, 919 KB

english, 2011

19

Limited infection upon human exposure to a recombinant raccoon pox vaccine vector

Tonie E Rocke, F.Joshua Dein, Martina Fuchsberger, Barry C Fox, Dan T Stinchcomb, Jorge E Osorio

Journal:

Year:

2004

Language:

english

File:

PDF, 79 KB

english, 2004

20

A method for determining two substrates binding in the same active site of cytochrome P450BM3: an explanation of high energy ω product formation

Dan A Rock, Brandon N.S Perkins, Jan Wahlstrom, Jeffrey P Jones

Journal:

Archives of Biochemistry and Biophysics

Year:

2003

Language:

english

File:

PDF, 159 KB

english, 2003

21

Recombinant raccoon pox vaccine protects mice against lethal plague

Jorge E Osorio, Tim D Powell, Rexann S Frank, Kelley Moss, Elizabeth J Haanes, Susan R Smith, Tonie E Rocke, Dan T Stinchcomb

Journal:

Year:

2003

Language:

english

File:

PDF, 213 KB

english, 2003

22

Differential Time-Dependent Inactivation of P450 3A4 and P450 3A5 by Raloxifene: A Key Role for C239 in Quenching Reactive Intermediates

Pearson, Josh T., Wahlstrom, Jan L., Dickmann, Leslie J., Kumar, Santosh, Halpert, James R., Wienkers, Larry C., Foti, Robert S., Rock, Dan A.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 308 KB

english, 2007

23

Time-Dependent Inactivation of P450 3A4 by Raloxifene: Identification of Cys239 as the Site of Apoprotein Alkylation 1

Baer, Brian R., Wienkers, Larry C., Rock, Dan A.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 275 KB

english, 2007

24

In Vitro Modulation of Cytochrome P450 Reductase Supported Indoleamine 2,3-Dioxygenase Activity by Allosteric Effectors Cytochrome b 5 and Methylene Blue

Pearson, Josh T., Siu, Sophia, Meininger, David P., Wienkers, Larry C., Rock, Dan A.

Journal:

Year:

2010

Language:

english

File:

PDF, 3.43 MB

english, 2010

25

Absolute Quantification of Aldehyde Oxidase Protein in Human Liver Using Liquid Chromatography–Tandem Mass Spectrometry

Barr, John T., Jones, Jeffrey P., Joswig-Jones, Carolyn A., Rock, Dan A.

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 1.17 MB

english, 2013

26

THE SEVERITY OF PULMONARY HYPERTENSION CORRELATES WITH WORSENING RENAL FUNCTION IN PATIENTS WITH PRESERVED SYSTOLIC FUNCTION

Rock-Willoughby, Jayme, Sheikh, Mujeeb, Sraow, Dan Inder, Khouri, Samer

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 92 KB

english, 2012

27

Benign Synthesis of 2-Ethylhexanoic Acid by Cytochrome P450cam: Enzymatic, Crystallographic, and Theoretical Studies †

French, Kevin J., Strickler, Michael D., Rock, Dan A., Rock, Denise A., Bennett, Grace A., Wahlstrom, Jan L., Goldstein, Barry M., Jones, Jeffrey P.

Journal:

Year:

2001

Language:

english

File:

PDF, 247 KB

english, 2001

28

Kinetic Isotope Effects Implicate the Iron−Oxene as the Sole Oxidant in P450-Catalyzed N-Dealkylation

Dowers, Tamara S., Rock, Dan A., Rock, Denise A., Jones, Jeffrey P.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 40 KB

english, 2004

29

Assessment of the Metabolism and Intrinsic Reactivity of a Novel Catechol Metabolite

Hutzler, J. Matthew, Melton, Roger J., Rumsey, Jeanne M., Thompson, David C., Rock, Dan A., Wienkers, Larry C.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 627 KB

english, 2008

30

Complex impedance measurements of calorimeters and bolometers: Correction for stray impedances

Lindeman, Mark. A., Barger, Kathleen A., Brandl, Donald E., Crowder, S. Gwynne, Rocks, Lindsay, McCammon, Dan

Journal:

Review of Scientific Instruments

Year:

2007

Language:

english

File:

PDF, 427 KB

english, 2007

31

Age at Vaccination May Influence Response to Sylvatic Plague Vaccine (SPV) in Gunnison’s Prairie Dogs (Cynomys gunnisoni)

Rocke, Tonie E., Tripp, Dan, Lorenzsonn, Faye, Falendysz, Elizabeth, Smith, Susan, Williamson, Judy, Abbott, Rachel

Journal:

Year:

2015

Language:

english

File:

PDF, 379 KB

english, 2015

32

Serepidemiology of Hepatitis B and D Virus Infection among Intravenous Drug Addicts in Israel

DAN, MICHAEL, ROCK, MEIR, LILOS, PEARL, SHANY, SHULAMIT BAR

Journal:

International Journal of Epidemiology

Year:

1993

Language:

english

File:

PDF, 263 KB

english, 1993

33

Bioanalytical approaches to assess the proteolytic stability of therapeutic fusion proteins

Pearson, Josh T, Rock, Dan A

Journal:

Year:

2015

Language:

english

File:

PDF, 3.09 MB

english, 2015

34

Intact Mass Analysis of Monoclonal Antibodies by Capillary Electrophoresis—Mass Spectrometry

Han, Mei, Rock, Brooke M., Pearson, Josh T., Rock, Dan A.

Journal:

Journal of Chromatography B

Year:

2015

Language:

english

File:

PDF, 959 KB

english, 2015

35

Incidence of symptom recurrence after hysterectomy for endometriosis*

Namnoum, Anne B., Hickman, Timothy N., Goodman, Sandra B., Gehlbach, Dan L., Rock, John A.

Journal:

Fertility and Sterility

Year:

1995

Language:

english

File:

PDF, 697 KB

english, 1995

36

Altering antibody drug conjugate binding to the Neonatal Fc Receptor impacts efficacy and tolerability

Hamblett, Kevin J., Le, Tiep, Rock, Brooke M., Rock, Dan A, Siu, Sophia, Huard, Justin N., Conner, Kip P., Milburn, Robert R., O`Neill, Jason W., Tometsko, Mark E., Fanslow, William C.

Journal:

Molecular Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.63 MB

english, 2016

37

The Milky Way’s Kiloparsec‐Scale Wind: A Hybrid Cosmic‐Ray and Thermally Driven Outflow

Everett, John E., Zweibel, Ellen G., Benjamin, Robert A., McCammon, Dan, Rocks, Lindsay, Gallagher III, John S.

Journal:

The Astrophysical Journal

Year:

2008

Language:

english

File:

PDF, 573 KB

english, 2008

38

[Society of Petroleum Engineers SPE/IADC Drilling Conference - (2005.02.23-2005.02.25)] Proceedings of SPE/IADC Drilling Conference - True Hybrid Operations Combining Coiled Tubing Drilling and Conventional Rig Workover Techniques and Practices

Cassee, Udo, Rock, Devin, Kara, Dan, McLaughlin, Sean

Year:

2005

Language:

english

File:

PDF, 459 KB

english, 2005

39

Immuno-affinity Capture followed by TMPP N-Terminus Tagging to Study Catabolism of Therapeutic Proteins

Kullolli, Majlinda, Rock, Dan A, Ma, Ji

Journal:

Journal of Proteome Research

Year:

2016

Language:

english

File:

PDF, 922 KB

english, 2016

40

SRM-based measurements of proprotein convertase subtilisin/kexin type 9 and lipoprotein(a) kinetics in nonhuman primate serum

Xie, Fang, Emery, Maurice G, Gibbs, John P, Rock, Dan A, Rock, Brooke M

Journal:

Year:

2016

Language:

english

File:

PDF, 1.49 MB

english, 2016

41

Reagent-free LC–MS/MS-based pharmacokinetic quantification of polyhistidine-tagged therapeutic proteins

Shi, Jianxia, Wong, Jing Man, Ma, Ji, Dickerson, Tiffany, Hall, Colin, Rock, Dan A, Carlson, Timothy J

Journal:

Year:

2017

Language:

english

File:

PDF, 2.31 MB

english, 2017

42

In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s

Wang, Zhican, Fang, Ying, Teague, Juli, Wong, Hansen, Morisseau, Christophe, Hammock, Bruce D., Rock, Dan A, Wang, Zhengping

Journal:

Drug Metabolism and Disposition

Year:

2017

Language:

english

File:

PDF, 715 KB

english, 2017

43

Development of a Translational Physiologically Based Pharmacokinetic Model for Antibody-Drug Conjugates: a Case Study with T-DM1

Khot, Antari, Tibbitts, Jay, Rock, Dan, Shah, Dhaval K.

Journal:

The AAPS Journal

Year:

2017

Language:

english

File:

PDF, 1.92 MB

english, 2017

44

Immunoaffinity capture coupled with capillary electrophoresis - mass spectrometry to study protein therapeutic stability in vivo

Han, Mei, Pearson, Josh T., Wang, Yunan, Winters, Dwight, Soto, Marcus, Rock, Dan A., Rock, Brooke M.

Journal:

Analytical Biochemistry

Year:

2017

Language:

english

File:

PDF, 1.19 MB

english, 2017

45

Rapid screening and characterization of glutathione-trapped reactive metabolites using a polarity switch-based approach on a high-resolution quadrupole orbitrap mass spectrometer

Wang, Zhican, Fang, Ying, Rock, Dan, Ma, Ji

Journal:

Analytical and Bioanalytical Chemistry

Year:

2017

Language:

english

File:

PDF, 984 KB

english, 2017

46

A quantitative method for detection of circulating Fms related tyrosine kinase 3 (FLT-3) in acute myeloid leukemia (AML) patients

Cook, Kevin D., Finger, Elizabeth C., Santos, Cedric Dos, Rock, Dan

Journal:

Journal of Immunological Methods

Year:

2019

Language:

english

File:

PDF, 542 KB

english, 2019

47

Preclinical characterization of the ADME properties of a surrogate anti-IL-36R monoclonal antibody antagonist in mouse serum and tissues

Conner, Kip P., Pastuskovas, Cinthia V., Soto, Marcus, Thomas, Veena A., Wagner, Mylo, Rock, Dan A.

Journal:

Year:

2020

File:

PDF, 4.32 MB

2020

48

Emerging siRNA design principles and consequences for biotransformation and disposition in drug development

Humphreys, Sara, Thayer, Mai, Campbell, Jabbar, Chen, Wen Li Kelly, Adams, Dan, Lade, Julie Maylor, Rock, Brooke M.

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.02 MB

2020

49

Mechanistic Studies of Cytochrome P450 3A4 Time Dependent Inhibition Using Two Cysteine- Targeting Electrophiles

Barr, John T, Wang, Zhican, Min, Xiaoshan, Wienkers, Henry J, Rock, Brooke M, Rock, Dan A, Wienkers, Larry C

Journal:

Drug Metabolism and Disposition

Year:

2020

File:

PDF, 4.27 MB

2020